Mother cells definition10/29/2023 ![]() (1995) Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Sasal, Y., Lu, B., Steinbelsser, H., and De Robertis, E. (2001) Embryo-derived stem cells: of mice and men. (2000) Stem cells: units of development, units of regeneration, and units in evolution. (2001) Nuclear cloning and epigenetic reprogramming of the genome. (2001) Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations. (2003) Transdifferentiation: fact or artifact. (1996) Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. (1993) Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia. (1992) Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. (2007) Current status of human embryonic stem cell research. (1998) Embryonic stem cell lines derived from human blastocysts. NSC-derived from human embryonic stem cell.Ways to produce well-defined populations, avoid oncogenicity, and ensure survival need to be clarified before clinical application can begin. However, the complexity of NSCs, neural patterning, and the formation of multiple populations of neurons, astrocytes, and oligodendrocytes warrant the need for intense studies to characterize these cells and to define the microenvironment that will be needed to support them in the diseased CNS. Human embryonic stem cells, with their ability for self-renewal, clonal capacity, normal karyotype, and potential to form NSCs, easily may be the best source of NSCs and progenitors for treating disease. Adult NSC and restricted progenitors are found in the several regions of the CNS throughout life. The neuroepithelial cells generate radial glia that produce fetal and adult NSCs within the central nervous system (CNS). Neural stem cells (NSCs) arise from embryonic ectoderm that forms neuroepithelial cells. Stem cells can be derived from early embryos after the formation of the blastocyst or from fetal, postnatal, or adult sources. There are also aspects of clonality and potency. The working definition of a stem cell includes self-renewal and the ability to differentiate into several cell types.
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